Nicotinic Acid

Nicotinic Acid

CAS No.: 59-67-6
Molecular Formula: C6H5NO2
Molecular weight: 123.11
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product description
Nicotinic Acid (Nicotinic Acid, also known as Vitamin B₃, CAS number 59-67-6, is extremely important in human metabolism, medicine and industry. Its molecular formula is (C_6H_5NO_2) and its molecular weight is 123.11. Chemical name pyridine-3-carboxylic acid, belongs to the pyridine derivatives. It is one of the 13 essential vitamins in the human body and is involved in many important metabolic processes in the body. In cell respiration, niacin constitutes the key components of coenzyme Ⅰ (NAD) and Coenzyme Ⅱ (NADP), and plays an irreplaceable role in the energy conversion of carbohydrates, fats and proteins, ensuring the normal operation of human tissues and organs.


Chemical Properties

PropertyValue

Melting point

236-239 °C(lit.)

Boiling point

260C

Density

1.473

Bulk density

330kg/m3

Refractive index

1.5423 (estimate)

Fp

193°C

Storage temp.

2-8°C

Solubility

18g/l

Pka

4.85(at 25℃)

Form

Powder

Color

White to off-white

PH

2.7 (18g/l, H2O, 20℃)

Odor

Odorless to sl. odor, sour taste

Biological source

synthetic (organic)

Water Solubility

1-5 g/100 mL at 17 ºC

Merck

14,6525

BRN

109591

BCS Class

3

Stability

Stable. Incompatible with strong oxidizing agents. May be light sensitive.

InChIKey

PVNIIMVLHYAWGP-UHFFFAOYSA-N

LogP

0.360

CAS DataBase Reference

59-67-6(CAS DataBase Reference)

NIST Chemistry Reference

Niacin(59-67-6)

EPA Substance Registry System

Nicotinic acid (59-67-6)


Safety Information

PropertyValue
Hazard symbolsXi, T, F
Hazard class codes36/37/38-36-39/23/24/25-23/24/25-11
Safety descriptions26-36-24/25-45-36/37-16-7
UN dangerous goods numberUN 1230 - class 3 - PG 2 - Methanol, solution
WGK Germany1
RTECS numberQT0525000
F8
Autoignition temperature>365 °C (Dust)
TSCATSCA listed
HS code29362990
Storage class11 - Combustible solids
Hazard class (category)Eye irritation, Category 2
Hazardous substances data59-67-6 (Hazardous Substances Data)
ToxicityLD50 s.c. in rats: 5 g/kg (Brazda, Coulson)


Product Usage

Nicotinic Acid, commonly known as Vitamin B3 or Niacin, is a vital nutrient with diverse applications across multiple industries. In the pharmaceutical and nutraceutical sectors, it is primarily used to treat pellagra and as a lipid-lowering agent to improve cholesterol profiles by reducing LDL and increasing HDL levels. Its role in the food industry is equally critical, where it serves as a fortification agent in cereals, flour, and infant formulas to prevent nutritional deficiencies. In the animal feed industry, it is an essential additive for livestock and poultry to promote healthy growth and metabolic efficiency. Furthermore, nicotinic acid is increasingly utilized in cosmetics and skincare (often as its derivative niacinamide) to enhance skin barrier function, improve elasticity, and even out skin tone.

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Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
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A1: Yes, our company holds a number of internationally recognized core certifications. All production and operation activities strictly follow international environmental, safety and quality standards, and each batch of products is accompanied by a compliance test report to meet the chemical industry requirements in different regions around the world.


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