D-α-Tocopherol succinate

D-α-Tocopherol succinate

CAS No.: 4345-03-3
Molecular Formula: C33H54O5
Molecular Weight: 530.78
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product description
Tocopherol succinate (4345-03-3) is a potent antioxidant.  Protects mice from gamma-radiation by induction of granulocyte-colony stimulating factor.1,2? Tocopherol succinate induces apoptosis in human gastric cancer cells3? and inhibits proliferation of mesothelioma cells by down-regulation of fibroblast growth factor receptor-14.  Induces apoptosis in neuroblastoma cells.5


Chemical Properties
PropertyValue

Melting point

~76 °C(lit.)

Boiling point

625.8±55.0 °C(Predicted)

Density

1.002±0.06 g/cm3(Predicted)

Vapor pressure

0Pa at 20℃

Storage temp.

-20°C

Solubility

Practically insoluble in water, very soluble in methylene chloride, soluble in acetone and in anhydrous ethanol.

Form

Solid

Pka

4.35±0.17(Predicted)

Color

White or off-white

Odor

Little or no odor

Biological source

synthetic

λmax

286nm(EtOH)(lit.)

Merck

14,9495

BRN

4038233

Specific Activity

1210IU/g

Stability

Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.

LogP

12 at 25℃

CAS DataBase Reference

4345-03-3(CAS DataBase Reference)

EPA Substance Registry System

D-.alpha.-Tocopheryl acid succinate (4345-03-3)


Safety Information

PropertyValue

WGK Germany

1

RTECS

EJ9984000

F

8-10-23

HS Code

2936280000

Toxicity

LD50 oral in rat: > 7gm/kg


Product Usage

D-α-Tocopherol succinate, a solid derivative of natural Vitamin E, is highly valued for its superior stability and potent biological activity. Its primary application is in the pharmaceutical and nutraceutical industries, where it is a preferred form of Vitamin E for high-end dietary supplements, tablets, and hard capsules due to its non-oily, crystalline nature. Beyond basic nutritional fortification, it is extensively researched and utilized for its anti-tumor properties and ability to induce apoptosis in cancer cells without harming normal tissues. In the cosmetic sector, it serves as a powerful antioxidant and skin-conditioning agent, protecting cell membranes from oxidative damage and UV-induced stress. Furthermore, it is used in functional foods and animal nutrition to enhance shelf life and support immune function, offering better resistance to heat and oxidation compared to liquid Vitamin E.

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Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
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Q1: Are Your Products Compliant With International Standards?

A1: Yes, our company holds a number of internationally recognized core certifications. All production and operation activities strictly follow international environmental, safety and quality standards, and each batch of products is accompanied by a compliance test report to meet the chemical industry requirements in different regions around the world.


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A2: Yes, we have a professional R&D team and refined production capacity. We can customize chemical products of different specifications and performances according to customers' specific needs, and provide full-process technical support to meet the personalized application needs of downstream industries.


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A3: The delivery cycle varies according to product type, order quantity and destination. We have a complete global supply chain system to ensure fast and safe delivery of goods. For specific cycle, you can consult our sales team for detailed information.


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A4: You can contact our customer service or sales team to specify the specific model and specification of the required samples. We will provide free samples according to the actual situation, and the sample express fee can be negotiated.

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