Arbutin

Arbutin

CAS No.: 497-76-7
Molecular Formula: C12H16O7
Molecular Weight: 272.25
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product description
Arbutin is a β-D-glucopyranoside HQ derivative and a plant-derived compound found in the dried leaves of several plant species, including blueberry, cranberry, bearberry, and pear trees. It suppresses tyrosinase activity without altering RNA expression.


Chemical Properties
PropertyValue

Melting point

195-198 °C

Alpha

-64 º (c=3)

Boiling point

375.31°C (rough estimate)

Density

1.3582 (rough estimate)

Refractive index

-65.5 ° (C=4, H2O)

Storage temp.

Inert atmosphere,Room Temperature

Solubility

H2O: 50 mg/mL hot, clear

Pka

10.10±0.15(Predicted)

Form

Solid

Color

White

Biological source

Synthetic or plant

Optical Rotation

[α]/D -64.0±2.0°, c = 3 in H2O

Water Solubility

10-15 g/100 mL at 20 ºC

Sensitive

Hygroscopic

Merck

14,773

BRN

89673

Stability

Stable. Hygroscopic - store under dry nitrogen.

InChIKey

BJRNKVDFDLYUGJ-RMPHRYRLSA-N

LogP

-1.350

CAS DataBase Reference

497-76-7(CAS DataBase Reference)

EPA Substance Registry System

.beta.-D-Glucopyranoside, 4-hydroxyphenyl (497-76-7)


Safety Information

PropertyValue

Hazard Codes

Xn

Risk Statements

20/21/22-36/37/38

Safety Statements

22-24/25-36-26

WGK Germany

3

RTECS

CE8863000

F

3-10-23

HS Code

29389090

Hazardous Substances Data

497-76-7(Hazardous Substances Data)


Product Usage

Arbutin, a naturally derived hydroquinone glucoside typically extracted from bearberry leaves, is a premier active ingredient in the global cosmetic and skincare industry. It is primarily utilized as a safe and effective skin-lightening agent in brightening serums, whitening creams, and spot-correction treatments. By competitively inhibiting tyrosinase activity, it effectively suppresses melanin production to fade hyperpigmentation, melasma, and post-inflammatory dark spots. In the personal care sector, Arbutin is highly valued for its dual functionality, offering both depigmenting effects and potent antioxidant properties that protect the skin against oxidative stress induced by UV radiation. Furthermore, its mild nature compared to synthetic alternatives makes it an ideal component for sensitive skin formulations and high-end dermo-cosmetics aimed at evening out skin tone and restoring a youthful, radiant complexion.

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Shipping And Transportation

Delivery Time

Inventory 2-3 working days New manufacturing 7-10 working days

Mode of Transportation
1. By Air, fast but expensive.
2. By Sea, usual and economy.
3. By Train, suit for middle Asia countries.
4. By Express, suit for small package.
We only provide highest quality goods available, accompanied by after support!

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Qualification Certificate
  • 微信图片_2026-04-09_153718_808
  • 微信图片_2026-04-09_153715_255
  • 微信图片_2026-04-09_153711_744
  • 微信图片_2026-04-09_153654_640
FAQ

Q1: Are Your Products Compliant With International Standards?

A1: Yes, our company holds a number of internationally recognized core certifications. All production and operation activities strictly follow international environmental, safety and quality standards, and each batch of products is accompanied by a compliance test report to meet the chemical industry requirements in different regions around the world.


Q2: Do You Provide Customized Product Services?
A2: Yes, we have a professional R&D team and refined production capacity. We can customize chemical products of different specifications and performances according to customers' specific needs, and provide full-process technical support to meet the personalized application needs of downstream industries.


Q3: What Is The Approximate Delivery Cycle Of The Products?
A3: The delivery cycle varies according to product type, order quantity and destination. We have a complete global supply chain system to ensure fast and safe delivery of goods. For specific cycle, you can consult our sales team for detailed information.


Q4: How To Obtain Product Samples?
A4: You can contact our customer service or sales team to specify the specific model and specification of the required samples. We will provide free samples according to the actual situation, and the sample express fee can be negotiated.

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